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Institute: Institute of Biological Chemistry, Academia Sinica
Faculty List
Andrew H.-J. Wang Chun-Hung Lin Chung-I Chang Guang-Chao Chen
Inn-Ho Tsai Kuan Wang Kay-Hooi Khoo Meng-Chiao Ho
Ming-Daw Tsai Po-Huang Liang Rita P.-Y. Chen Shang-Te Danny Hsu
Shih-Hsiung Wu Shui-Tein Chen Tzu-Ching Meng Wei-Yuan Yang
Yu-Ling Shih
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Andrew H.-J. Wang

Tel ˇG(02) 2785-5696 x1010

(02) 2785-5696 x5010

FaxˇG(02) 2788-2043

ahjwang@gate.sinica.edu.tw
ResearchˇG
Structure and function of biological macromolecules, including both proteins and nucleic acids; structures and dynamics of nucleic acids; molecular basis of anticancer drug-DNA interactions; proteomics; protein-nucleic acid interactions; structures of proteins from extremophiles
Chun-Hung Lin

Tel ˇG(02) 2785-5696 x6010

FaxˇG(02) 2651-4705

chunhung@gate.sinica.edu.tw
ResearchˇG
Enzyme-catalyzed synthesis; cloning and over-expression of enzymes for organic synthesis; mechanistic studies of enzymatic reactions; carbohydrate synthesis; structure & function of complex carbohydrates; design, synthesis, and evaluation of inhibitors and new drugs
Chung-I Chang

Tel ˇG(02) 2785-5696 x7110

(02) 2785-5696 x7070

FaxˇG(02) 2788-9759

chungi@gate.sinica.edu.tw
ResearchˇG
Structural Biology, Protein Engineering, Structure-Based Drug Discovery.
Guang-Chao Chen

Tel ˇG(02) 2785-5696 x7010

FaxˇG(02) 2788-9759

gcchen@gate.sinica.edu.tw
ResearchˇG
Rho family GTPase signaling pathways in Drosophila developmental morphogenesis. Functional analysis of focal adhesion proteins in development and tumorigenesis
Inn-Ho Tsai

Tel ˇG(02) 2362-0261 x2011

(02) 2362-0261 x2031

FaxˇG(02) 2363-5038

bc201@gate.sinica.edu.tw
ResearchˇG
Biochemistry of proteins, including plasma proteins, zinc-metalloproteases and serine proteases of snake venoms; and neurotoxic phospholipase A2
Kay-Hooi Khoo

Tel ˇG(02) 2785-5696 x6030

FaxˇG(02) 2788-9759

kkhoo@gate.sinica.edu.tw
ResearchˇG
Analytical techniques in glycobiology; application of mass-spectrometry and separation techniques in structural mapping and sequencing of complex glycans; structure, biosynthesis, and functions of immunogenic glycoconjugates in bacterial and parasitic infections with applications to the development of iagnostics, drug and vaccine design
Kuan Wang

Tel ˇG(02) 2785-5696 x5120

FaxˇG(02) 2788-9759

wangk@gate.sinica.edu.tw
ResearchˇG
Muscle Biology and Physiology, Muscle Disease, Traction Systems Structural Biology, Muscle Proteinomics, Nanotechnology
Meng-Chiao Ho

Tel ˇG(02) 2785-5696

FaxˇG(02) 2788-9759

josephho77@gmail.com
ResearchˇG
Structure-activity studies of pharmaceutically important enzymes, protein crystallography, drug design.
Ming-Daw Tsai

Tel ˇG(02) 2789-9930 x247

FaxˇG(02) 2789-9931

Tsai@chemistry.ohio-state.edu
ResearchˇG
Structure and functional relationship in tumor suppressor, DNA polymerase/ligase, FHA domain containing proteins and phospholipase.
Po-Huang Liang

Tel ˇG(02) 2785-5696 x6070

FaxˇG(02) 2788-9759

phliang@gate.sinica.edu.tw
ResearchˇG
Purification, cloning and expression of novel enzymes and proteins; studies of enzyme inhibitors; characterization of protein-protein interactions using biophysical tools such as stopped-flow, surface plasmon resonance, isothermal titration, calorimetry, analytical ultracentrifuge
Rita P.-Y. Chen

Tel ˇG(02) 2785-5696 x5040

FaxˇG(02) 2788-9759

pyc@gate.sinica.edu.tw
ResearchˇG
Protein folding: Study how a protein can fold into its native structure using various biophysical tools like NMR, CD, FTIR, stopped-flow apparatus, laser flash photolysis; Protein misfolding: Study how proteins misfold and cause diseases like mad cow disease
Shang-Te Danny Hsu

Tel ˇG(02) 2785-5696 x3060

FaxˇG(02) 2788-9759

hsushangte@gmail.com
ResearchˇG
Molecular Biophysics, protein folding and misfolding, NMR spectroscopy.
Shih-Hsiung Wu

Tel ˇG(02) 2785-5696 x7101

FaxˇG(02) 2788-9759

shwu@gate.sinica.edu.tw
ResearchˇG
Carbohydrate chemistry and glycobiology; preparation of chiral or other useful intermediates by chemoenzymatic methods; determination of tertiary structures of peptides and proteins by NMR spectroscopy and molecular modeling
Shui-Tein Chen

Tel ˇG(02) 2785-5696 x7071

FaxˇG(02) 2788-9759

bcchen@gate.sinica.edu.tw
ResearchˇG
The deployment of enzymes in organic synthesis; the use of chemical approaches in protein engineering; drug delivery and targeting
Tzu-Ching Meng

Tel ˇG(02) 2785-5696 x6140

FaxˇG(02) 2788-9759

tcmeng@gate.sinica.edu.tw
ResearchˇG
Signal transduction, tyrosine phosphorylation and dephosphorylation, functions of protein tyrosine phosphoatases, and regulation of tyrosine phosphatases by reversible oxidation
Wei-Yuan Yang

Tel ˇG(02) 2785-5696 x8031

FaxˇG(02) 2788-9759

weiyang@gate.sinica.edu.tw
ResearchˇG
Live cell imaging and optogenetics approaches to autophagy research. Single molecule studies.
Yu-Ling Shih

Tel ˇG(02) 2785-5696 x7020

FaxˇG(02) 2788-9759

ylshih10@gate.sinica.edu.tw
ResearchˇG
Mechanisms of spatial and temporal control of bacterial cell division and functional study of bacterial cytoskeletons.

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